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| カタログ番号 | HT386014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PDE2A (Asp241-Gln387). | ||||||||
| ターゲット | cGMP-dependent 3', 5'-cyclic phosphodiesterase, CGS-PDE, PDE2A, cGSPDE, Cyclic GMP-stimulated phosphodiesterase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O00408 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A) is a ~105 kDa protein. cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. Plays a role in cell growth and migration. 1. Iffland, A. et al. (2005) Biochemistry 44, 8312-25. PMID: 15938621 2. Salpietro, V. et al. (2018) Movement disorders : official journal of the Movement Disorder Society 33, 482-488. PMID: 29392776 3. Rosman, GJ. et al. (1997) Gene 191, 89-95. PMID: 9210593 4. Hiramoto, K. et al. (2014) Cellular signalling 26, 1807-17. PMID: 24705027 | ||||||||
| 注意事項 | For research use only. |
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