

| Número de catálogo | HW319014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PDE6B (Met1-Gly198). | ||||||||
| Objetivo | GMP-PDE beta, PDEB, Rod cGMP-specific 3', 5'-cyclic phosphodiesterase subunit beta, PDE6B | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P35913 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B) is a ~98 kDa protein. Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal. 1. Muradov, H. et al. (2010) The Journal of biological chemistry 285, 39828-34. PMID: 20940301 2. McLaughlin, ME. et al. (1993) Nature genetics 4, 130-4. PMID: 8394174 | ||||||||
| Nota | For research use only. |
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