Anti-Human PDE8A Polyclonal Antibody (HD652014)

Name: Anti-Human PDE8A Polyclonal Antibody
Brand: abinScience
SKU: HD652014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HD652014

Description

Anti-Human PDE8A Polyclonal Antibody (HD652014) is a rabbit polyclonal antibody detecting PDE8A. Suitable for Human.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human PDE8A (Ser480-Glu829).

Cible

EC:3.1.4.53, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O60658

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A) is a ~93 kDa protein. Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine.

1. Wang, H. et al. (2008) Biochemistry 47, 12760-8. PMID: 18983167

2. Brown, KM. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, E1533-42. PMID: 23509299

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human PDE8A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human PDE8A Polyclonal Antibody (HD652014)

Aperçu

Images

Reférences

Fiche technique

SDS