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| カタログ番号 | HW764014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PEX19 Polyclonal Antibody (HW764014) is a rabbit polyclonal antibody detecting PEX19 in ELISA, IHC, WB. Suitable for Human, Rat.
Highlights
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| 種反応性 | Human, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PEX19 (Glu98-His263). | ||||||||
| ターゲット | Peroxisomal biogenesis factor 19, Peroxisomal farnesylated protein, Peroxin-19, PEX19, PXF, 33 kDa housekeeping protein, HK33 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P40855 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Peroxisomal biogenesis factor 19 (PEX19) is a ~32 kDa protein. Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | ||||||||
| 注意事項 | For research use only. |
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