Anti-Human PEX5 Polyclonal Antibody (HW731014)

Name: Anti-Human PEX5 Polyclonal Antibody
Brand: abinScience
SKU: HW731014
Price: 96 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW731014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human PEX5 (His306-Gln639).

Cible

Peroxisomal targeting signal 1 receptor, PTS1 receptor, PTS1-BP, PTS1R, Peroxin-5, Peroxisome receptor 1, PXR1, PEX5, Peroxisomal C-terminal targeting signal import receptor

Purification

Purified by antigen affinity column.

Numéro d'accès

P50542

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Peroxisomal targeting signal 1 receptor (PEX5/PTS1) is a ~70 kDa protein. Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type). Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins. PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.

1. Gatto, GJ. et al. (2000) Nature structural biology 7, 1091-5. PMID: 11101887

2. Dammai, V. et al. (2001) Cell 105, 187-96. PMID: 11336669

3. Harper, CC. et al. (2003) The Journal of biological chemistry 278, 7897-901. PMID: 12456682

4. Miyata, N. et al. (2005) Molecular and cellular biology 25, 10822-32. PMID: 16314507

5. Stanley, WA. et al. (2006) Molecular cell 24, 653-663. PMID: 17157249

6. Stanley, WA. et al. (2007) BMC structural biology 7, 24. PMID: 17428317

7. Freitas, MO. et al. (2011) The Journal of biological chemistry 286, 40509-19. PMID: 21976670

8. Zhang, J. et al. (2015) Nature cell biology 17, 1259-1269. PMID: 26344566

9. Fransen, M. et al. (1995) The Journal of biological chemistry 270, 7731-6. PMID: 7706321

10. Dodt, G. et al. (1995) Nature genetics 9, 115-25. PMID: 7719337

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PEX5 polyclonal antibody at 1μg/ml on various samples.
Lane 1: 293T cell lysate
Lane 2: Mouse brain lysate
Lane 3: Rat brain lysate

Reférences

Fiche technique

Anti-Human PEX5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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