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Anti-Human PGRMC1 Polyclonal Antibody (HT051014)

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Número de catálogoHT051014
Descripción
Anti-Human PGRMC1 Polyclonal Antibody (HT051014) is a rabbit polyclonal antibody detecting PGRMC1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PGRMC1 (Pro75-Asp195).
Objetivo PGRMC, mPR, IZA, Membrane-associated progesterone receptor component 1, HPR6.6, Dap1, PGRMC1
Purificación Purified by antigen affinity column.
Número de acceso O00264
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Membrane-associated progesterone receptor component 1 (PGRMC1) is a ~21 kDa protein. Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone.

1. Ryu, CS. et al. (2017) Frontiers in pharmacology 8, 159. PMID: 28396637
2. Kaluka, D. et al. (2015) Biochemistry 54, 1638-47. PMID: 25675345
3. Piel, RB. et al. (2016) Biochemistry 55, 5204-17. PMID: 27599036
4. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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