

| Numéro de catalogue | HT051014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PGRMC1 Polyclonal Antibody (HT051014) is a rabbit polyclonal antibody detecting PGRMC1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PGRMC1 (Pro75-Asp195). | ||||||||
| Cible | PGRMC, mPR, IZA, Membrane-associated progesterone receptor component 1, HPR6.6, Dap1, PGRMC1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O00264 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Membrane-associated progesterone receptor component 1 (PGRMC1) is a ~21 kDa protein. Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. 1. Ryu, CS. et al. (2017) Frontiers in pharmacology 8, 159. PMID: 28396637 2. Kaluka, D. et al. (2015) Biochemistry 54, 1638-47. PMID: 25675345 3. Piel, RB. et al. (2016) Biochemistry 55, 5204-17. PMID: 27599036 4. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021 | ||||||||
| Note | For research use only. |
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