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| カタログ番号 | HT051014 | ||||||||
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| 説明 |
Anti-Human PGRMC1 Polyclonal Antibody (HT051014) is a rabbit polyclonal antibody detecting PGRMC1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PGRMC1 (Pro75-Asp195). | ||||||||
| ターゲット | PGRMC, mPR, IZA, Membrane-associated progesterone receptor component 1, HPR6.6, Dap1, PGRMC1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O00264 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Membrane-associated progesterone receptor component 1 (PGRMC1) is a ~21 kDa protein. Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. 1. Ryu, CS. et al. (2017) Frontiers in pharmacology 8, 159. PMID: 28396637 2. Kaluka, D. et al. (2015) Biochemistry 54, 1638-47. PMID: 25675345 3. Piel, RB. et al. (2016) Biochemistry 55, 5204-17. PMID: 27599036 4. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021 | ||||||||
| 注意事項 | For research use only. |
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