Anti-Human PHF8 IP Recombinant Antibody (SAA0216) (HP682013)

Name: Anti-Human PHF8 IP Recombinant Antibody (SAA0216)
Brand: abinScience
SKU: HP682013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP682013

Reactividad de especies

Human

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a

ID de clon

SAA0216

Objetivo

[histone H3]-dimethyl-L-lysine(9) demethylase PHF8, KIAA1111, [histone H3]-dimethyl-L-lysine(36) demethylase PHF8, PHF8, ZNF422, Histone lysine demethylase PHF8, PHD finger protein 8

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9UPP1

RRID

Anti-Human PHF8 IP Antibody (SAA0216) (abinScience Cat# HP682013, RRID:AB_3729750)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Histone lysine demethylase PHF8 is a ~117 kDa protein. Histone lysine demethylase with selectivity for mono- and dimethylated residues. It plays an essential role in cell cycle progression and rDNA transcription. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Displays a very low intrinsic activity toward dimethylated H3 'Lys-27' (H3K27Me2).

1. Loenarz, C. et al. (2010) Human molecular genetics 19, 217-22. PMID: 19843542

2. Zhu, Z. et al. (2010) Cell research 20, 794-801. PMID: 20531378

3. Qiu, J. et al. (2010) Cell research 20, 908-18. PMID: 20548336

4. Liu, W. et al. (2010) Nature 466, 508-12. PMID: 20622854

5. Yu, L. et al. (2010) Cell research 20, 166-73. PMID: 20101266

6. Feng, W. et al. (2010) Nature structural & molecular biology 17, 445-50. PMID: 20208542

7. Kleine-Kohlbrecher, D. et al. (2010) Molecular cell 38, 165-78. PMID: 20346720

8. Qi, HH. et al. (2010) Nature 466, 503-7. PMID: 20622853

9. Horton, JR. et al. (2010) Nature structural & molecular biology 17, 38-43. PMID: 20023638

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human PHF8 IP Antibody (SAA0216)

Referencias

Datasheet

Anti-Human PHF8 IP Recombinant Antibody (SAA0216).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo