Anti-Human PHF8 IP Recombinant Antibody (SAA0216) (HP682013)

Name: Anti-Human PHF8 IP Recombinant Antibody (SAA0216)
Brand: abinScience
SKU: HP682013
Price: 191 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HP682013

Reactivité des espèces

Human

Applications

ELISA, IF, IP

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a

ID de clone

SAA0216

Cible

[histone H3]-dimethyl-L-lysine(9) demethylase PHF8, KIAA1111, [histone H3]-dimethyl-L-lysine(36) demethylase PHF8, PHF8, ZNF422, Histone lysine demethylase PHF8, PHD finger protein 8

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9UPP1

RRID

Anti-Human PHF8 IP Antibody (SAA0216) (abinScience Cat# HP682013, RRID:AB_3729750)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Histone lysine demethylase PHF8 is a ~117 kDa protein. Histone lysine demethylase with selectivity for mono- and dimethylated residues. It plays an essential role in cell cycle progression and rDNA transcription. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Displays a very low intrinsic activity toward dimethylated H3 'Lys-27' (H3K27Me2).

1. Loenarz, C. et al. (2010) Human molecular genetics 19, 217-22. PMID: 19843542

2. Zhu, Z. et al. (2010) Cell research 20, 794-801. PMID: 20531378

3. Qiu, J. et al. (2010) Cell research 20, 908-18. PMID: 20548336

4. Liu, W. et al. (2010) Nature 466, 508-12. PMID: 20622854

5. Yu, L. et al. (2010) Cell research 20, 166-73. PMID: 20101266

6. Feng, W. et al. (2010) Nature structural & molecular biology 17, 445-50. PMID: 20208542

7. Kleine-Kohlbrecher, D. et al. (2010) Molecular cell 38, 165-78. PMID: 20346720

8. Qi, HH. et al. (2010) Nature 466, 503-7. PMID: 20622853

9. Horton, JR. et al. (2010) Nature structural & molecular biology 17, 38-43. PMID: 20023638

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PHF8 IP Antibody (SAA0216)

Reférences

Fiche technique

Anti-Human PHF8 IP Recombinant Antibody (SAA0216).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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