

| Número de catálogo | HP530014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PIH1D1 (Glu15-Ser181). | ||||||||
| Objetivo | Nucleolar protein 17 homolog, PIH1D1, PIH1 domain-containing protein 1, NOP17 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9NWS0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | PIH1 domain-containing protein 1 (PIH1D1) is a ~32 kDa protein. Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex. 1. McKeegan, KS. et al. (2007) Molecular and cellular biology 27, 6782-93. PMID: 17636026 2. Zhai, N. et al. (2012) Journal of molecular cell biology 4, 231-41. PMID: 22368283 3. Kamano, Y. et al. (2013) FEBS letters 587, 3303-8. PMID: 24036451 4. Horejsí, Z. et al. (2010) Molecular cell 39, 839-50. PMID: 20864032 | ||||||||
| Nota | For research use only. |
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