Anti-Human Coagulation Factor II Monoclonal Antibody (1A302) (HF621025)

Name: Anti-Human Coagulation Factor II Monoclonal Antibody (1A302)
Brand: abinScience
SKU: HF621025
Price: 194 USD
Availability: InStock

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Numéro de catalogue	HF621025
Description	Anti-Human PIVKA-II/DCP Monoclonal Antibody (1A302) [1A302] (HF621025) is a mouse monoclonal antibody detecting Coagulation factor II in ELISA. Suitable for Human.
Reactivité des espèces	Human
Applications	ELISA
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG
ID de clone	1A302
Immunogène	Human PIVKA-II/DCP Protein.
Cible	Prothrombin, 3.4.21.5, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P00734
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Prothrombin (F2/PIVKA-II) is a ~70 kDa protein. Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation factor XI (F11); activation is promoted by the contact with negatively charged surfaces. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells. 1. Naito, K. et al. (1991) The Journal of biological chemistry 266, 7353-8. PMID: 2019570 2. Choi, SH. et al. (2011) Blood 118, 6963-70. PMID: 21976677 3. Shinozawa, E. et al. (2018) Frontiers in pharmacology 9, 1431. PMID: 30568593 4. Senden, NH. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 161, 4318-24. PMID: 9780208
Note	For research use only.

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SDS-PAGE for Anti-Human PIVKA-II/DCP Monoclonal Antibody (1A302)

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Anti-Human Coagulation Factor II Monoclonal Antibody (1A302).pdf

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Anti-Human Coagulation Factor II Monoclonal Antibody (1A302) (HF621025)

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