Anti-Human Coagulation Factor II Monoclonal Antibody (1A302) (HF621025)

Name: Anti-Human Coagulation Factor II Monoclonal Antibody (1A302)
Brand: abinScience
SKU: HF621025
Price: 194 USD
Availability: InStock

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Каталожный номер	HF621025
Описание	Anti-Human PIVKA-II/DCP Monoclonal Antibody (1A302) [1A302] (HF621025) is a mouse monoclonal antibody detecting Coagulation factor II in ELISA. Suitable for Human.
Реактивность видов	Human
Применения	ELISA
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG
ID клона	1A302
Иммуноген	Human PIVKA-II/DCP Protein.
Цель	Prothrombin, 3.4.21.5, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P00734
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Prothrombin (F2/PIVKA-II) is a ~70 kDa protein. Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation factor XI (F11); activation is promoted by the contact with negatively charged surfaces. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells. 1. Naito, K. et al. (1991) The Journal of biological chemistry 266, 7353-8. PMID: 2019570 2. Choi, SH. et al. (2011) Blood 118, 6963-70. PMID: 21976677 3. Shinozawa, E. et al. (2018) Frontiers in pharmacology 9, 1431. PMID: 30568593 4. Senden, NH. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 161, 4318-24. PMID: 9780208
Примечание	For research use only.

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SDS-PAGE for Anti-Human PIVKA-II/DCP Monoclonal Antibody (1A302)

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Anti-Human Coagulation Factor II Monoclonal Antibody (1A302).pdf

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Anti-Human Coagulation Factor II Monoclonal Antibody (1A302) (HF621025)

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