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Anti-Human PKM Recombinant Antibody (SAA1958) (HB819013)

Anti-Human PKM Recombinant Antibody (SAA1958)
Anti-Human PKM Recombinant Antibody (SAA1958)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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  • Vista general

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  • Datasheet

  • SDS

Vista general
Número de catálogoHB819013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1958
Objetivo PK2, Opa-interacting protein 3, THBP1, Tumor M2-PK, PKM, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, PK3, Pyruvate kinase 2/3, p58, CTHBP, PKM2, Pyruvate kinase PKM, OIP-3, Cytosolic thyroid hormone-binding protein, OIP3
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P14618
RRID

Anti-Human PKM Antibody (SAA1958) (abinScience Cat# HB819013, RRID:AB_3727722)
_x005F_x005F_x000D_

Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Pyruvate kinase PKM is a ~57 kDa protein. Catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

1. Dombrauckas, JD. et al. (2005) Biochemistry 44, 9417-29. PMID: 15996096
2. Ashizawa, K. et al. (1991) Biochemistry 30, 7105-11. PMID: 1854723
3. Vander Heiden, MG. et al. (2010) Science (New York, N.Y.) 329, 1492-9. PMID: 20847263
Nota For research use only.
Imágenes
  • Anti-Human PKM Recombinant Antibody (SAA1958)

    SDS-PAGE

    SDS-PAGE for Anti-Human PKM Antibody (SAA1958)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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