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Anti-Human PLA2G10 Polyclonal Antibody (HT102014)

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Vista general
Número de catálogoHT102014
Descripción
Anti-Human PLA2G10 Polyclonal Antibody (HT102014) is a rabbit polyclonal antibody detecting PLA2G10. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PLA2G10 (Glu32-Asp165).
Objetivo EC:3.1.1.4, GX sPLA2, Group 10 secretory phospholipase A2, Group X secretory phospholipase A2, PLA2G10, Phosphatidylcholine 2-acylhydrolase 10, sPLA2-X
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O15496
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Group 10 secretory phospholipase A2 (PLA2G10) is a ~18 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles. Hydrolyzes LDL phospholipids releasing unsaturated fatty acids that regulate macrophage differentiation toward foam cells.

1. Hanasaki, K. et al. (2002) The Journal of biological chemistry 277, 29116-24. PMID: 12021277
2. Cupillard, L. et al. (1997) The Journal of biological chemistry 272, 15745-52. PMID: 9188469
3. Singer, AG. et al. (2002) The Journal of biological chemistry 277, 48535-49. PMID: 12359733
4. Gora, S. et al. (2006) Biochimica et biophysica acta 1761, 1093-9. PMID: 16962371
5. Koduri, RS. et al. (2002) The Journal of biological chemistry 277, 5849-57. PMID: 11694541
6. Mitsuishi, M. et al. (2006) The Biochemical journal 393, 97-106. PMID: 16146426
Nota For research use only
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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