Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

Name: Anti-Human PLA2G5 Polyclonal Antibody
Brand: abinScience
SKU: HA627014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Número de catálogo

HA627014

Descripción

Anti-Human PLA2G5 Polyclonal Antibody (HA627014) is a rabbit polyclonal antibody detecting Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human PLA2G5 (Gly21-Ser138).

Objetivo

Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P39877

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Phospholipase A2 group V (PLA2G5) is a ~15 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups. Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype. May act in an autocrine and paracrine manner. Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.

1. Chen, J. et al. (1994) The Journal of biological chemistry 269, 2365-8. PMID: 8300559

2. Sun, YX. et al. (2004) The Biochemical journal 380, 749-56. PMID: 14998370

3. Hsu, YH. et al. (2013) PloS one 8, e59267. PMID: 23533611

4. Rubio, JM. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 3327-39. PMID: 25725101

5. Koduri, RS. et al. (2002) The Journal of biological chemistry 277, 5849-57. PMID: 11694541

6. Kim, YJ. et al. (2002) The Journal of biological chemistry 277, 36479-88. PMID: 12124392

7. Muñoz, NM. et al. (2003) The Journal of biological chemistry 278, 38813-20. PMID: 12796497

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human PLA2G5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

Vista general

Imágenes

Referencias

Datasheet

SDS