Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

Name: Anti-Human PLA2G5 Polyclonal Antibody
Brand: abinScience
SKU: HA627014
Price: 168 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA627014

Description

Anti-Human PLA2G5 Polyclonal Antibody (HA627014) is a rabbit polyclonal antibody detecting Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human PLA2G5 (Gly21-Ser138).

Cible

Phospholipase A2 group V; 3.1.1.4; PLA2-10; Phosphatidylcholine 2-acylhydrolase 5; PLA2G5

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P39877

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Phospholipase A2 group V (PLA2G5) is a ~15 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups. Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype. May act in an autocrine and paracrine manner. Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.

1. Chen, J. et al. (1994) The Journal of biological chemistry 269, 2365-8. PMID: 8300559

2. Sun, YX. et al. (2004) The Biochemical journal 380, 749-56. PMID: 14998370

3. Hsu, YH. et al. (2013) PloS one 8, e59267. PMID: 23533611

4. Rubio, JM. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 3327-39. PMID: 25725101

5. Koduri, RS. et al. (2002) The Journal of biological chemistry 277, 5849-57. PMID: 11694541

6. Kim, YJ. et al. (2002) The Journal of biological chemistry 277, 36479-88. PMID: 12124392

7. Muñoz, NM. et al. (2003) The Journal of biological chemistry 278, 38813-20. PMID: 12796497

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human PLA2G5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human PLA2G5 Polyclonal Antibody (HA627014)

Aperçu

Images

Reférences

Fiche technique

SDS