Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959) (HC624013)

Name: Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959)
Brand: abinScience
SKU: HC624013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC624013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1959

Cible

PLA2R, 180 kDa secretory phospholipase A2 receptor, Secretory phospholipase A2 receptor, PLA2-R, M-type receptor, C-type lectin domain family 13 member C, Soluble PLA2-R, PLA2R1, Soluble PLA2R, CLEC13C

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q13018

RRID

Anti-Human PLA2R1/PLA2R Antibody (SAA1959) (abinScience Cat# HC624013, RRID:AB_3727723)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Secretory phospholipase A2 receptor (PLA2R1/PLA2R) is a ~168 kDa protein. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells.

1. Granata, F. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 464-74. PMID: 15611272

2. Ancian, P. et al. (1995) The Journal of biological chemistry 270, 8963-70. PMID: 7721806

3. Pan, Y. et al. (2014) Scientific reports 4, 6660. PMID: 25335547

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PLA2R1/PLA2R Antibody (SAA1959)

Reférences

Fiche technique

Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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