Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959) (HC624013)

Name: Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959)
Brand: abinScience
SKU: HC624013
Price: 196 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HC624013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1959

Цель

PLA2R, 180 kDa secretory phospholipase A2 receptor, Secretory phospholipase A2 receptor, PLA2-R, M-type receptor, C-type lectin domain family 13 member C, Soluble PLA2-R, PLA2R1, Soluble PLA2R, CLEC13C

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q13018

RRID

Anti-Human PLA2R1/PLA2R Antibody (SAA1959) (abinScience Cat# HC624013, RRID:AB_3727723)
_x005F_x005F_x000D_

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Secretory phospholipase A2 receptor (PLA2R1/PLA2R) is a ~168 kDa protein. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells.

1. Granata, F. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 464-74. PMID: 15611272

2. Ancian, P. et al. (1995) The Journal of biological chemistry 270, 8963-70. PMID: 7721806

3. Pan, Y. et al. (2014) Scientific reports 4, 6660. PMID: 25335547

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human PLA2R1/PLA2R Antibody (SAA1959)

Ссылки

Даташит

Anti-Human PLA2R1/PLA2R Recombinant Antibody (SAA1959).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа