

| Каталожный номер | HA520014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human PLAG1 Polyclonal Antibody (HA520014) is a rabbit polyclonal antibody detecting PLAG1 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Gallus gallus, Mus musculus, and Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human PLAG1 (Gly26-Thr245). | ||||||||
| Цель | PLAG1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q6DJT9 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Альтернативные названия | Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1 | ||||||||
| Фон | Zinc finger protein PLAG1 is a ~55 kDa protein. Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia. | ||||||||
| Примечание | For research use only. |
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