

| Número de catálogo | HA090014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human PLK3 Polyclonal Antibody (HA090014) is a rabbit polyclonal antibody detecting PLK3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PLK3 (Thr426-Ala646). | ||||||||
| Objetivo | FGF-inducible kinase, FNK, PLK-3, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/threonine-protein kinase, PLK3, PRK, CNK, Polo-like kinase 3, Proliferation-related kinase | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9H4B4 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Serine/threonine-protein kinase PLK3 is a ~71 kDa protein. Serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly. Polo-like kinases act by binding and phosphorylating proteins that are already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates ATF2, BCL2L1, CDC25A, CDC25C, CHEK2, HIF1A, JUN, p53/TP53, p73/TP73, PTEN, TOP2A and VRK1. Involved in cell cycle regulation: required for entry into S phase and cytokinesis. Phosphorylates BCL2L1, leading to regulate the G2 checkpoint and progression to cytokinesis during mitosis. | ||||||||
| Nota | For research use only. |

Lane 1: Hela cell lysate
Lane 2: H1299 cell lysate
Lane 3: K562 cell lysate
Lane 4: 293T cell lysate
Lane 5: A549 cell lysate
Lane 6: SKOV3 cell lysate
Lane 7: Mouse brain lysate
Lane 8: Mouse spleen lysate
Lane 9: Rat brain lysate
Lane 10: Rat heart lysate
Lane11: Rat spleen lysate
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