Anti-Human PLOD3 Polyclonal Antibody (HT299014)

Name: Anti-Human PLOD3 Polyclonal Antibody
Brand: abinScience
SKU: HT299014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HT299014

Description

Anti-Human PLOD3 Polyclonal Antibody (HT299014) is a rabbit polyclonal antibody detecting PLOD3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human PLOD3 (Asn35-Asn255).

Cible

LH3, Lysyl hydroxylase 3, Procollagen galactosyltransferase, Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, Galactosylhydroxylysine-glucosyltransferase, PLOD3, Procollagen glucosyltransferase

Purification

Purified by antigen affinity column.

Numéro d'accès

O60568

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) is a ~84 kDa protein. Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine. Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues.

1. Rautavuoma, K. et al. (2002) The Journal of biological chemistry 277, 23084-91. PMID: 11956192

2. Wang, C. et al. (2002) Matrix biology : journal of the International Society for Matrix Biology 21, 559-66. PMID: 12475640

3. Wang, C. et al. (2009) Journal of cellular and molecular medicine 13, 508-21. PMID: 18298658

4. Salo, AM. et al. (2008) American journal of human genetics 83, 495-503. PMID: 18834968

5. Scietti, L. et al. (2018) Nature communications 9, 3163. PMID: 30089812

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human PLOD3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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