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| カタログ番号 | HT299014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PLOD3 Polyclonal Antibody (HT299014) is a rabbit polyclonal antibody detecting PLOD3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PLOD3 (Asn35-Asn255). | ||||||||
| ターゲット | LH3, Lysyl hydroxylase 3, Procollagen galactosyltransferase, Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, Galactosylhydroxylysine-glucosyltransferase, PLOD3, Procollagen glucosyltransferase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60568 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) is a ~84 kDa protein. Multifunctional enzyme that catalyzes a series of essential post-translational modifications on Lys residues in procollagen. Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine. Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues. Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues. 1. Rautavuoma, K. et al. (2002) The Journal of biological chemistry 277, 23084-91. PMID: 11956192 2. Wang, C. et al. (2002) Matrix biology : journal of the International Society for Matrix Biology 21, 559-66. PMID: 12475640 3. Wang, C. et al. (2009) Journal of cellular and molecular medicine 13, 508-21. PMID: 18298658 4. Salo, AM. et al. (2008) American journal of human genetics 83, 495-503. PMID: 18834968 5. Scietti, L. et al. (2018) Nature communications 9, 3163. PMID: 30089812 | ||||||||
| 注意事項 | For research use only. |
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