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Anti-Human PLXNB1 Polyclonal Antibody (HT264024)

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Vista general
Número de catálogoHT264024
Descripción
Anti-Human PLXNB1 Polyclonal Antibody (HT264024) is a rabbit polyclonal antibody detecting PLXNB1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PLXNB1 (Cys1067-Asp1251).
Objetivo SEP, Semaphorin receptor SEP, PLXN5, PLXNB1, Plexin-B1, KIAA0407
Purificación Purified by antigen affinity column.
Número de acceso O43157
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Plexin-B1 (PLXNB1) is a ~232 kDa protein. Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.

1. Tong, Y. et al. (2009) The Journal of biological chemistry 284, 35962-72. PMID: 19843518
2. Janssen, BJ. et al. (2010) Nature 467, 1118-22. PMID: 20877282
3. Bell, CH. et al. (2011) PLoS biology 9, e1001134. PMID: 21912513
4. Aurandt, J. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 12085-90. PMID: 12196628
5. Swiercz, JM. et al. (2004) The Journal of cell biology 165, 869-80. PMID: 15210733
6. Giordano, S. et al. (2002) Nature cell biology 4, 720-4. PMID: 12198496
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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