Anti-Human PNPT1 Polyclonal Antibody (HC241014)

Name: Anti-Human PNPT1 Polyclonal Antibody
Brand: abinScience
SKU: HC241014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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SDS

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Número de catálogo

HC241014

Descripción

Anti-Human PNPT1 Polyclonal Antibody (HC241014) is a rabbit polyclonal antibody detecting PNPT1. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human PNPT1 (Gly43-Lys595).

Objetivo

3'-5' RNA exonuclease OLD35, EC:2.7.7.8, PNPASE, PNPT1, PNPase 1, PNPase old-35, Polynucleotide phosphorylase 1, Polynucleotide phosphorylase-like protein, Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q8TCS8

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) is a ~85 kDa protein. RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules.

1. Pietras, Z. et al. (2018) Nature communications 9, 2558. PMID: 29967381

2. Kim, S. et al. (2024) Molecular cell 84, 2935-2948.e7. PMID: 39019044

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human PNPT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human PNPT1 Polyclonal Antibody (HC241014)

Vista general

Imágenes

Referencias

Datasheet

SDS