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Anti-Human POFUT2 Polyclonal Antibody (HA070014)

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Aperçu
Numéro de catalogueHA070014
Description
Anti-Human POFUT2 Polyclonal Antibody (HA070014) is a rabbit polyclonal antibody detecting POFUT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human POFUT2 (Pro53-Tyr167).
Cible POFUT2, FUT13, Peptide-O-fucosyltransferase 2, GDP-fucose protein O-fucosyltransferase 2, KIAA0958, C21orf80, O-FucT-2
Purification Purified by antigen affinity column.
Numéro d'accès Q9Y2G5
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

GDP-fucose protein O-fucosyltransferase 2 (POFUT2) is a ~49 kDa protein. GDP-fucose protein O-fucosyltransferase involved in one of the two pathways responsible for protein O-linked fucosylation, a unique post-translational modification of cysteine-knotted proteins that regulates various biological functions. This pathway targets proteins with Thrombospondin type-1 (TSP1) repeats (TSR) in the endoplasmic reticulum. Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS, the thrombospondin (TSP) and spondin families (Probable). Required for the proper secretion of ADAMTS family members such as ADAMTSL1 and ADAMTS13.

1. Chen, CI. et al. (2012) The EMBO journal 31, 3183-97. PMID: 22588082
2. Wang, LW. et al. (2007) The Journal of biological chemistry 282, 17024-31. PMID: 17395588
3. Ricketts, LM. et al. (2007) The Journal of biological chemistry 282, 17014-23. PMID: 17395589
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human POFUT2 Polyclonal Antibody

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