Anti-Human PPP1CC Polyclonal Antibody (HW554014)

Name: Anti-Human PPP1CC Polyclonal Antibody
Brand: abinScience
SKU: HW554014
Price: 96 USD
Availability: InStock

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Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW554014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human PPP1CC (Met1-Lys323).

Objetivo

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC

Purificación

Purified by antigen affinity column.

Número de acceso

P36873

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) is a ~36 kDa protein. Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.

1. Djouder, N. et al. (2007) Molecular cell 28, 28-40. PMID: 17936702

2. Takagi, M. et al. (2014) The Journal of biological chemistry 289, 22877-22887. PMID: 25012651

3. Lee, JH. et al. (2010) The Journal of biological chemistry 285, 24466-76. PMID: 20516061

4. Schmutz, I. et al. (2011) PloS one 6, e21325. PMID: 21712997

5. Sivakumar, S. et al. (2017) Biology open 6, 1672-1679. PMID: 28982702

6. Nie, H. et al. (2013) Nature medicine 19, 322-8. PMID: 23396208

7. Wies, E. et al. (2013) Immunity 38, 437-49. PMID: 23499489

8. Liau, NPD. et al. (2022) Nature 609, 400-407. PMID: 35768504

9. Kwon, JJ. et al. (2022) Nature 609, 408-415. PMID: 35831509

Nota

For research use only.

Imágenes

Western blot

Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate

Referencias

Datasheet

Anti-Human PPP1CC Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo