Anti-Human PPP1CC Polyclonal Antibody (HW554014)

Name: Anti-Human PPP1CC Polyclonal Antibody
Brand: abinScience
SKU: HW554014
Price: 96 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW554014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human PPP1CC (Met1-Lys323).

Cible

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC

Purification

Purified by antigen affinity column.

Numéro d'accès

P36873

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) is a ~36 kDa protein. Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.

1. Djouder, N. et al. (2007) Molecular cell 28, 28-40. PMID: 17936702

2. Takagi, M. et al. (2014) The Journal of biological chemistry 289, 22877-22887. PMID: 25012651

3. Lee, JH. et al. (2010) The Journal of biological chemistry 285, 24466-76. PMID: 20516061

4. Schmutz, I. et al. (2011) PloS one 6, e21325. PMID: 21712997

5. Sivakumar, S. et al. (2017) Biology open 6, 1672-1679. PMID: 28982702

6. Nie, H. et al. (2013) Nature medicine 19, 322-8. PMID: 23396208

7. Wies, E. et al. (2013) Immunity 38, 437-49. PMID: 23499489

8. Liau, NPD. et al. (2022) Nature 609, 400-407. PMID: 35768504

9. Kwon, JJ. et al. (2022) Nature 609, 408-415. PMID: 35831509

Note

For research use only.

Images

Western blot

Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate

Reférences

Fiche technique

Anti-Human PPP1CC Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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