

| Número de catálogo | HD625014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human PPP1R11 Polyclonal Antibody (HD625014) is a rabbit polyclonal antibody detecting PPP1R11. Suitable for Human and Rat.
Highlights
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| Reactividad de especies | Human, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PPP1R11 (Arg26-His126). | ||||||||
| Objetivo | E3 ubiquitin-protein ligase PPP1R11, EC:2.3.2.27, HCG V, HCGV, Hemochromatosis candidate gene V protein, PPP1R11, Protein phosphatase 1 regulatory subunit 11, Protein phosphatase inhibitor 3, TCTE5 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O60927 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | E3 ubiquitin-protein ligase PPP1R11 is a ~13 kDa protein. Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. 1. McKelvey, AC. et al. (2016) eLife 5. PMID: 27805901 2. Zhang, J. et al. (1998) Biochemistry 37, 16728-34. PMID: 9843442 | ||||||||
| Nota | For research use only |
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