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Anti-Human PPP1R11 Polyclonal Antibody (HD625014)

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  • 100ug
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Vista general
Número de catálogoHD625014
Descripción
Anti-Human PPP1R11 Polyclonal Antibody (HD625014) is a rabbit polyclonal antibody detecting PPP1R11. Suitable for Human and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PPP1R11 (Arg26-His126).
Objetivo E3 ubiquitin-protein ligase PPP1R11, EC:2.3.2.27, HCG V, HCGV, Hemochromatosis candidate gene V protein, PPP1R11, Protein phosphatase 1 regulatory subunit 11, Protein phosphatase inhibitor 3, TCTE5
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso O60927
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

E3 ubiquitin-protein ligase PPP1R11 is a ~13 kDa protein. Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1.

1. McKelvey, AC. et al. (2016) eLife 5. PMID: 27805901
2. Zhang, J. et al. (1998) Biochemistry 37, 16728-34. PMID: 9843442
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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