

| Numéro de catalogue | HA024014 | ||||||||
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| Description |
Anti-Human PRAP1 Polyclonal Antibody (HA024014) is a rabbit polyclonal antibody detecting Proline-rich acidic protein 1; Epididymis tissue protein Li 178; Uterine-specific proline-rich acidic protein; PRAP1; UPA; UNQ608/PRO1195 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human PRAP1 (Val21-Gln151). | ||||||||
| Cible | Proline-rich acidic protein 1; Epididymis tissue protein Li 178; Uterine-specific proline-rich acidic protein; PRAP1; UPA; UNQ608/PRO1195 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96NZ9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Proline-rich acidic protein 1 (PRAP1) is a ~17 kDa protein. Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas. 1. Zhang, J. et al. (2003) Cancer research 63, 6658-65. PMID: 14583459 2. Huang, BH. et al. (2012) Cell death & disease 3, e442. PMID: 23235459 3. Sze, KM. et al. (2014) The Journal of pathology 233, 51-60. PMID: 24374861 | ||||||||
| Note | For research use only |




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