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Anti-Human PRDX1 Polyclonal Antibody (HC366014)

Anti-Human PRDX1 Polyclonal Antibody
Anti-Human PRDX1 Polyclonal Antibody
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Vista general
Número de catálogoHC366014
Descripción
Anti-Human PRDX1 Polyclonal Antibody (HC366014) is a rabbit polyclonal antibody detecting PRDX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cricetulus griseus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PRDX1 (Lys16-Lys199).
Objetivo Thioredoxin-dependent peroxide reductase 2, PAGB, Thioredoxin peroxidase 2, Proliferation-associated gene protein, Thioredoxin-dependent peroxiredoxin 1, PAG, PAGA, Peroxiredoxin-1, Natural killer cell-enhancing factor A, TDPX2, NKEF-A, PRDX1
Purificación Purified by antigen affinity column.
Número de acceso Q06830
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Peroxiredoxin-1 (PRDX1) is a ~22 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.

1. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6297-302. PMID: 9497357
Nota For research use only.
Imágenes
  • Anti-Human PRDX1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-PRDX1 polyclonal antibody at 1μg/ml on various samples.
    Lane 1: HepG2 cell lysate
    Lane 2: A549 cell lysate
    Lane 3: MCF7 cell lysate
    Lane 4: Jurkat cell lysate
    Lane 5: Mouse kidney lysate

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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