

| Numéro de catalogue | HC366014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PRDX1 Polyclonal Antibody (HC366014) is a rabbit polyclonal antibody detecting PRDX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cricetulus griseus.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PRDX1 (Lys16-Lys199). | ||||||||
| Cible | Thioredoxin-dependent peroxide reductase 2, PAGB, Thioredoxin peroxidase 2, Proliferation-associated gene protein, Thioredoxin-dependent peroxiredoxin 1, PAG, PAGA, Peroxiredoxin-1, Natural killer cell-enhancing factor A, TDPX2, NKEF-A, PRDX1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q06830 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Peroxiredoxin-1 (PRDX1) is a ~22 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. 1. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6297-302. PMID: 9497357 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PRDX1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: A549 cell lysate
Lane 3: MCF7 cell lysate
Lane 4: Jurkat cell lysate
Lane 5: Mouse kidney lysate
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