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Anti-Human PRDX6 Polyclonal Antibody (HB999014)

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Vista general
Número de catálogoHB999014
Descripción
Anti-Human PRDX6 Polyclonal Antibody (HB999014) is a rabbit polyclonal antibody detecting PRDX6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PRDX6 (Met1-Pro224).
Objetivo 24 kDa protein, Lysophosphatidylcholine acyltransferase 5, Acidic calcium-independent phospholipase A2, KIAA0106, LPCAT-5, 1-Cys PRX, Antioxidant protein 2, LPC acyltransferase 5, aiPLA2, Non-selenium glutathione peroxidase, Lyso-PC acyltransferase 5, PRDX6, AOP2, Glutathione-dependent peroxiredoxin, Peroxiredoxin-6, NSGPx, Red blood cells page spot 12, 1-Cys peroxiredoxin, Liver 2D page spot 40
Purificación Purified by antigen affinity column.
Número de acceso P30041
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Peroxiredoxin-6 (PRDX6) is a ~25 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

1. Chen, JW. et al. (2000) The Journal of biological chemistry 275, 28421-7. PMID: 10893423
2. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6303-11. PMID: 9497358
3. Fisher, AB. et al. (2016) Journal of lipid research 57, 587-96. PMID: 26830860
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human PRDX6 Polyclonal Antibody

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