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| カタログ番号 | HC777014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PRKX Polyclonal Antibody (HC777014) is a rabbit polyclonal antibody detecting PRKX. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PRKX (Ser45-Arg301). | ||||||||
| ターゲット | EC:2.7.11.1, PKX1, PRKX, PrKX, Protein kinase PKX1, Protein kinase X, Protein kinase X-linked, Serine/threonine-protein kinase PRKX, cAMP-dependent protein kinase catalytic subunit PRKX | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P51817 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | cAMP-dependent protein kinase catalytic subunit PRKX is a ~40 kDa protein. Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation. | ||||||||
| 注意事項 | For research use only |
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