

| Número de catálogo | HD153014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human PRPF6 Polyclonal Antibody (HD153014) is a rabbit polyclonal antibody detecting PRPF6. Suitable for Rat, Human, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human PRPF6 (Lys606-Phe941). | ||||||||
| Objetivo | ANT-1, Androgen receptor N-terminal domain-transactivating protein 1, C20orf14, PRP6 homolog, PRPF6, Pre-mRNA-processing factor 6, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O94906 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Pre-mRNA-processing factor 6 (PRPF6) is a ~106 kDa protein. Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. 1. Schneider, M. et al. (2010) Nature structural & molecular biology 17, 216-21. PMID: 20118938 2. Tanackovic, G. et al. (2011) American journal of human genetics 88, 643-9. PMID: 21549338 3. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 | ||||||||
| Nota | For research use only |

Western blot analysis was performed using anti-PRPF6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: HL-60 cell lysate
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