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Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111) (HF561013)

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Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)
Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)
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Aperçu
Numéro de catalogueHF561013
Description
Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111) (HF561013) is a mouse monoclonal antibody detecting PSMD10/Gankyrin in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA2111
Cible 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, Gankyrin, p28(GANK), PSMD10
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès O75832
RRID Anti-Human PSMD10/Gankyrin Antibody (SAA2111) (abinScience Cat# HF561013, RRID:AB_3729456)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

26S proteasome non-ATPase regulatory subunit 10 (PSMD10/Gankyrin) is a ~24 kDa protein. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.

Note For research use only.
Isotype Control Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Images
  • Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)

    SDS-PAGE

    SDS-PAGE for Anti-Human PSMD10/Gankyrin Antibody (SAA2111)

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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