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Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111) (HF561013)

Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)
Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)
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Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерHF561013
Описание
Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111) (HF561013) is a mouse monoclonal antibody detecting PSMD10/Gankyrin in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Реактивность видовHuman
ПримененияELISA
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG2a, kappa
ID клонаSAA2111
Цель 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, Gankyrin, p28(GANK), PSMD10
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа O75832
RRID Anti-Human PSMD10/Gankyrin Antibody (SAA2111) (abinScience Cat# HF561013, RRID:AB_3729456)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

26S proteasome non-ATPase regulatory subunit 10 (PSMD10/Gankyrin) is a ~24 kDa protein. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.

Примечание For research use only.
Isotype Control Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Изображения
  • Anti-Human PSMD10/Gankyrin Recombinant Antibody (SAA2111)

    SDS-PAGE

    SDS-PAGE for Anti-Human PSMD10/Gankyrin Antibody (SAA2111)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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Working Solution
C₂ (Working Conc.)
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