Anti-Human PTGES3/P23 Polyclonal Antibody (HS799014)

Name: Anti-Human PTGES3/P23 Polyclonal Antibody
Brand: abinScience
SKU: HS799014
Price: 96 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HS799014

説明

Anti-Human PTGES3/P23 Polyclonal Antibody (HS799014) is a rabbit polyclonal antibody detecting PTGES3/P23 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human PTGES3/P23 (Met1-Glu160).

ターゲット

PTGES3, Hsp90 co-chaperone, P23, Progesterone receptor complex p23, Prostaglandin E synthase 3, cPGES, Telomerase-binding protein p23, Cytosolic prostaglandin E2 synthase, TEBP

精製

Purified by antigen affinity column.

アクセッション番号

Q15185

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Prostaglandin E synthase 3 (PTGES3/P23) is a ~18 kDa protein. Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

1. Tanioka, T. et al. (2000) The Journal of biological chemistry 275, 32775-82. PMID: 10922363

2. Forsythe, HL. et al. (2001) The Journal of biological chemistry 276, 15571-4. PMID: 11274138

3. Freeman, BC. et al. (2002) Science (New York, N.Y.) 296, 2232-5. PMID: 12077419

4. Song, D. et al. (2014) The Journal of biological chemistry 289, 14656-65. PMID: 24711448

注意事項

For research use only.

イメージ

Western blot

Lane 1: A549 cell lysate
Lane 2: PC-3 cell lysate
Lane 3: Hela cell lysate
Lane 4: HepG2 cell lysate
Lane 5: NIH3T3 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse testis lysate
Lane 8: Mouse brain lysate
Lane 9: Mouse spleen lysate
Lane 10: Rat testis lysate
Lane11: Rat brain lysate

参考文献

データシート

Anti-Human PTGES3/P23 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human PTGES3/P23 Polyclonal Antibody (HS799014)

概要

イメージ

参考文献

データシート

SDS