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Anti-Human PTPRN2 Polyclonal Antibody (HV238014)

Anti-Human PTPRN2 Polyclonal Antibody
Anti-Human PTPRN2 Polyclonal Antibody
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Aperçu
Numéro de catalogueHV238014
Description
Anti-Human PTPRN2 Polyclonal Antibody (HV238014) is a rabbit polyclonal antibody detecting PTPRN2 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca nemestrina, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human PTPRN2 (Cys839-Gln1015).
Cible PTPRN2
Purification Purified by antigen affinity column.
Numéro d'accès Q92932
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsReceptor-type tyrosine-protein phosphatase N2, R-PTP-N2, 3.1.3.-, 3.1.3.48, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, IA-2beta60, PTPRN2, KIAA0387
Contexte

Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) is a ~111 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain.

1. Sengelaub, CA. et al. (2016) The EMBO journal 35, 62-76. PMID: 26620550
Note For research use only.
Images
  • Anti-Human PTPRN2 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-PTPRN2 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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