

| Numéro de catalogue | HV238014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PTPRN2 Polyclonal Antibody (HV238014) is a rabbit polyclonal antibody detecting PTPRN2 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca nemestrina, Mus musculus, and Human.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PTPRN2 (Cys839-Gln1015). | ||||||||
| Cible | PTPRN2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q92932 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, 3.1.3.-, 3.1.3.48, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, IA-2beta60, PTPRN2, KIAA0387 | ||||||||
| Contexte | Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) is a ~111 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. 1. Sengelaub, CA. et al. (2016) The EMBO journal 35, 62-76. PMID: 26620550 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PTPRN2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
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