

| Каталожный номер | HV238014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human PTPRN2 Polyclonal Antibody (HV238014) is a rabbit polyclonal antibody detecting PTPRN2 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca nemestrina, Mus musculus, and Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human PTPRN2 (Cys839-Gln1015). | ||||||||
| Цель | PTPRN2 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q92932 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Альтернативные названия | Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, 3.1.3.-, 3.1.3.48, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, IA-2beta60, PTPRN2, KIAA0387 | ||||||||
| Фон | Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) is a ~111 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. 1. Sengelaub, CA. et al. (2016) The EMBO journal 35, 62-76. PMID: 26620550 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-PTPRN2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
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