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Anti-Human PCPTP1 Polyclonal Antibody (HA962014)

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Vista general
Número de catálogoHA962014
Descripción
Anti-Human PTPRQ Polyclonal Antibody (HA962014) is a rabbit polyclonal antibody detecting PTPRQ in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PTPRQ (Arg1929-Met2299).
Objetivo Phosphatidylinositol phosphatase PTPRQ, R-PTP-Q, PTP-RQ, PTPRQ, Receptor-type tyrosine-protein phosphatase Q
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by antigen affinity column.
Número de acceso Q9UMZ3
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Phosphatidylinositol phosphatase PTPRQ is a ~260 kDa protein. Dephosphorylates phosphatidylinositol phosphates, such as phosphatidylinositol 3,4,5-trisphosphate (PIP3) and phosphatidylinositol 3,5-diphosphates, with preference for PIP3. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity in vitro; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by regulating the levels of PIP3 in MSCs and preadipocyte cells.

1. Yu, KR. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 1522-9. PMID: 23897475
2. Jung, H. et al. (2009) Biochemical and biophysical research communications 383, 252-7. PMID: 19351528
3. Shahin, H. et al. (2010) Journal of medical genetics 47, 643-5. PMID: 20472657
4. Eisenberger, T. et al. (2018) Genetics in medicine : official journal of the American College of Medical Genetics 20, 614-621. PMID: 29309402
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human PCPTP1 Polyclonal Antibody

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