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Anti-Human PTPRS Recombinant Antibody (SAA1668) (HC306013)

Anti-Human PTPRS Recombinant Antibody (SAA1668)
Anti-Human PTPRS Recombinant Antibody (SAA1668)
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Aperçu
Numéro de catalogueHC306013
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA1668
Cible R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q13332
RRID Anti-Human PTPRS Antibody (SAA1668) (abinScience Cat# HC306013, RRID:AB_3727429)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Receptor-type tyrosine-protein phosphatase S (PTPRS) is a ~217 kDa protein. Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb.

1. Coles, CH. et al. (2011) Science (New York, N.Y.) 332, 484-8. PMID: 21454754
2. Pulido, R. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 11686-90. PMID: 8524829
3. Bunin, A. et al. (2015) Immunity 43, 277-88. PMID: 26231120
Note For research use only.
Images
  • Anti-Human PTPRS Recombinant Antibody (SAA1668)

    SDS-PAGE

    SDS-PAGE for Anti-Human PTPRS Antibody (SAA1668)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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