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| カタログ番号 | HC306013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1668 | ||||
| ターゲット | R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q13332 | ||||
| RRID | Anti-Human PTPRS Antibody (SAA1668) (abinScience Cat# HC306013, RRID:AB_3727429) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Receptor-type tyrosine-protein phosphatase S (PTPRS) is a ~217 kDa protein. Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb. 1. Coles, CH. et al. (2011) Science (New York, N.Y.) 332, 484-8. PMID: 21454754 2. Pulido, R. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 11686-90. PMID: 8524829 3. Bunin, A. et al. (2015) Immunity 43, 277-88. PMID: 26231120 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human PTPRS Antibody (SAA1668)
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