

| Каталожный номер | HC306013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a, kappa | ||||
| ID клона | SAA1668 | ||||
| Цель | R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q13332 | ||||
| RRID | Anti-Human PTPRS Antibody (SAA1668) (abinScience Cat# HC306013, RRID:AB_3727429) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Receptor-type tyrosine-protein phosphatase S (PTPRS) is a ~217 kDa protein. Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb. 1. Coles, CH. et al. (2011) Science (New York, N.Y.) 332, 484-8. PMID: 21454754 2. Pulido, R. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 11686-90. PMID: 8524829 3. Bunin, A. et al. (2015) Immunity 43, 277-88. PMID: 26231120 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human PTPRS Antibody (SAA1668)
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