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Anti-Human PYCR1 Polyclonal Antibody (HW791014)

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Vista general
Número de catálogoHW791014
Descripción
Anti-Human PYCR1 Polyclonal Antibody (HW791014) is a rabbit polyclonal antibody detecting PYCR1 in ELISA, IHC, WB. Suitable for Bovine, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PYCR1 (Met1-Asp319).
Objetivo PYCR1
Purificación Purified by antigen affinity column.
Número de acceso P32322
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosPyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, 1.5.1.2, PYCR1
Fondo

Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress.

1. Meng, Z. et al. (2006) Journal of molecular biology 359, 1364-77. PMID: 16730026
2. Reversade, B. et al. (2009) Nature genetics 41, 1016-21. PMID: 19648921
3. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808
4. Christensen, EM. et al. (2017) The Journal of biological chemistry 292, 7233-7243. PMID: 28258219
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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