

| Numéro de catalogue | HW791014 | ||||||||
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| Description |
Anti-Human PYCR1 Polyclonal Antibody (HW791014) is a rabbit polyclonal antibody detecting PYCR1 in ELISA, IHC, WB. Suitable for Bovine, Mus musculus, and Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PYCR1 (Met1-Asp319). | ||||||||
| Cible | PYCR1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P32322 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, 1.5.1.2, PYCR1 | ||||||||
| Contexte | Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress. 1. Meng, Z. et al. (2006) Journal of molecular biology 359, 1364-77. PMID: 16730026 2. Reversade, B. et al. (2009) Nature genetics 41, 1016-21. PMID: 19648921 3. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808 4. Christensen, EM. et al. (2017) The Journal of biological chemistry 292, 7233-7243. PMID: 28258219 | ||||||||
| Note | For research use only. |
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