

| Numéro de catalogue | HA292014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PYCR2 Polyclonal Antibody (HA292014) is a rabbit polyclonal antibody detecting PYCR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PYCR2 (Met1-Lys276). | ||||||||
| Cible | Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, 1.5.1.2, PYCR2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96C36 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Pyrroline-5-carboxylate reductase 2 (PYCR2) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). 1. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808 2. Merrill, MJ. et al. (1989) The Journal of biological chemistry 264, 9352-8. PMID: 2722838 3. Yeh, GC. et al. (1981) The Journal of clinical investigation 67, 1042-6. PMID: 6894153 4. Nakayama, T. et al. (2015) American journal of human genetics 96, 709-19. PMID: 25865492 | ||||||||
| Note | For research use only. |
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