Anti-Human RAB14 Polyclonal Antibody (HX042014)

Name: Anti-Human RAB14 Polyclonal Antibody
Brand: abinScience
SKU: HX042014
Price: 168 USD
Availability: InStock

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100ug

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX042014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human RAB14 (Met1-Ser180).

Cible

RAB14, Ras-related protein Rab-14

Purification

Purified by antigen affinity column.

Numéro d'accès

P61106

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Ras-related protein Rab-14 (RAB14) is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB14 is involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes.

1. Linford, A. et al. (2012) Developmental cell 22, 952-66. PMID: 22595670

2. Yamamoto, H. et al. (2010) Molecular biology of the cell 21, 2746-55. PMID: 20534812

3. Lall, P. et al. (2015) The Journal of biological chemistry 290, 18817-32. PMID: 26032412

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human RAB14 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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