

| Каталожный номер | HP286014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human RAB22A Polyclonal Antibody (HP286014) is a rabbit polyclonal antibody detecting RAB22A in ELISA, IHC, WB. Suitable for Human, Mouse, and Dog.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RAB22A (Met1-Ala171). | ||||||||
| Цель | RAB22A, RAB22, Ras-related protein Rab-22A, Rab-22 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9UL26 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras-related protein Rab-22A (RAB22A) is a ~21 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB22A plays a role in endocytosis and intracellular protein transport. Mediates trafficking of transferrin/TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. 1. Magadán, JG. et al. (2006) Molecular and cellular biology 26, 2595-614. PMID: 16537905 2. Wang, L. et al. (2011) Molecular biology of the cell 22, 3853-60. PMID: 21849477 | ||||||||
| Примечание | For research use only. |
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