

| Numéro de catalogue | HD629014 | ||||||||
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| Description |
Anti-Human RAB26 Polyclonal Antibody (HD629014) is a rabbit polyclonal antibody detecting RAB26. Suitable for Mouse, Human, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human RAB26 (Asp61-Pro256). | ||||||||
| Cible | EC:3.6.5.2, RAB26, Ras-related protein Rab-26 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9ULW5 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Ras-related protein Rab-26 (RAB26) is a ~27 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. 1. Li, C. et al. (2012) The Journal of biological chemistry 287, 42784-94. PMID: 23105096 2. Tian, X. et al. (2010) Molecular and cellular biology 30, 1269-84. PMID: 20038531 | ||||||||
| Note | For research use only |
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